IDH1 R132H

IDH1 R132H

648.002,834.00

Isocitrate Dehydrogenase 1 (IDH1) is a soluble, cytosolic enzyme involved in the TCA metabolic cycle. The most notable mutation in this enzyme, R132H, is clinically indicated in the majority of astrocytomas and oligodendroglial tumours, with the mutation being associated with more favourable prognosis and increased survival in those patients. IDH1 R132H is also useful in the differential diagnosis between anaplastic glioma and glioblastoma.

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IDH1-R132H-IHC132-Astrocytoma 0.1ml - IHC132-100 648.00
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IDH1-R132H-IHC132-Astrocytoma 1ml - IHC132-1 2,834.00
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IDH1-R132H-IHC132-Astrocytoma Positive Control 3 Slides - IHC132-PC 1,328.00
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Description

CE-IVD registered and supplied as a concentrate.   

Specifications

Clone IHC132
Source Mouse Monoclonal
Positive Control Astrocytoma
Dilution Range 1:100 – 1:200

References

  1. Cui D, et al. Int J Biochem Cell Biol. 2016;71:72-81.
  2. Balss J, et al. Acta Neuropathol. 2008; 116:597-602.
  3. Capper D, et al. Brain Pathol. 2010; 20:245-54.
  4. Camelo-Piragua S, et al. Acta Neuropathol. 2010; 119:509-11.

Additional information

Unit

0.1ml, 1ml, Positive Control 3 slides

Documents

Instructions for Use

Safety Data Sheet

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