p63

p63

648.002,834.00

p63 is a tumor suppressor protein that is very similar to p53 in structure and function, while being homologous to p73. p63 is important in development and differentiation, and has been identified as a useful marker for distinguishing between lung squamous cell carcinomas and adenocarcinomas. Anti-p63 is also used to differentiate between benign and malignant prostate and breast lesions, due to its labeling of the nuclei of myoepithelial cells in both tissue types.
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Image Variation SKU Price Quantity Add To Cart
0.1ml - IHC404-100-1 648.00
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1ml - IHC404-1-1 2,834.00
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Positive Control 3 Slides - IHC404-PC-1 866.00
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Description

CE-IVD registered and supplied as a concentrate.

Specifications

Clone IHC063
Source Mouse Monoclonal
Positive Control Skin, Squamous Cell Carcinoma, Prostate
Dilution Range 1:100 – 1:200

References

  1. Yang A, et al. Mol Cell. 1998; 2:305-16.
  2. Signoretti S, et al. Am J Pathol. 2000; 157:1769-75.
  3. Yang A, et al. Nature. 1999; 398:714-8.
  4. Barbareschi M, et al. Am J Surg Pathol. 2001; 25:1054-60.
  5. Werling RW, et al. Am J Surg Pathol. 2003; 27:82-90.
  6. Rajal B Shah, et al. Am J Surg Pathol. 2002; 26:1161-8.
  7. Iacono ML, et al. J Thorac Oncol. 2011; 6:473-81.
  8. Mukhopadhyay S, et al. Am J Surg Pathol. 2011; 35:15-25.
  9. Conde E, et al. PLoS One. 2010; 5:e12209.
  10. Uke M, et al. Cytopathology. 2010; 21:56-63.

Additional information

Units

0.1ml, 1ml, Positive Control 3 slides

Documents

Safety Data Sheet

Instructions for Use

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