SALL4

SALL4

278.001,196.00

Sal-Like Protein 4 (SALL4), is a zinc finger transcription factor found in germ cells and human blood progenitor cells, with functional involvement in modulating Oct-4 to maintain embryonic stem cell pluripotency. SALL4 is a useful marker for acute myeloid leukemia, B-cell acute lymphocytic leukemia, intratubular germ cell neoplasia, seminomas/dysgerminomas, and yolk sac tumors (both pediatric and postpubertal). Anti-SALL4 is used to detect embryonal carcinomas, hepatocellular carcinoma (HCC), gliomas, ovarian primitive germ-cell tumors, choriocarcinomas, spermatogonia, teratoma, gastric cancer, breast cancer, and lung cancer. Expression of SALL4 is often associated with poor prognosis in HCC, and with metastasis in endometrial cancer, colorectal carcinoma, and esophageal squamous cell carcinoma.

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Image Variation SKU Price Quantity Add To Cart
SALL4-IHC659-Testicular-Cancer 0.1ml - IHC659-100 278.00
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SALL4-IHC659-Testicular-Cancer 1ml - IHC659-1 1,196.00
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SALL4-IHC659-Testicular-Cancer Positive Control - IHC659-PC 770.00
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Description

CE-IVD registered and supplied as a concentrate.

Specifications

Clone IHC659
Source Mouse Monoclonal
Positive Control Seminoma, Dysgerminoma
Dilution Range 1:100 – 1:200

References

  1. Ma Y, et al. Blood. 2006; 108:2726-35.
  2. de Celis JF, et al. Int J Dev Biol. 2009; 53:1385–98.
  3. Kohlhase J, et al. Hum Mutat. 2005; 26:176–83.
  4. Miettinen M, et al. Am J Surg Pathol. 2014; 38:410–20.
  5. Zhang X, et al. Cancer Lett. 2015; 357:55–62.
  6. Ueno S, et al. Exp Hematol. 2014; 42:307–16.
  7. Cao D, et al. Am J Surg Pathol. 2009; 33:1065–77.
  8. Zhang L, et al. Oncogene. 2014; 33:5491–500.
  9. Kobayashi D, et al. Int J Oncol. 2011; 38:933–9.
  10. Cui W, et. al. Mod Pathol. 2006; 19:1585-92.
  11. Cao D, et al. Am J Surg Pathol. 2009; 33:894-904.

Additional information

Unit

0.1ml, 1ml, Positive Control

Documents

Instructions for Use

Safety Data Sheet

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